Transcription Factor BORIS (Brother of the Regulator of Imprinted Sites) Directly Induces Expression of a Cancer-Testis Antigen, TSP50, through Regulated Binding of BORIS to the Promoter

Cancer-testis antigens (CTAs) are normally expressed in testis but are aberrantly expressed in a variety of cancers with varying frequency. More than 100 proteins have been identified as CTA including testes-specific protease 50 (TSP50) and the testis-specific paralogue of CCCTC-binding factor, BORI...

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Hlavní autoři: Kosaka-Suzuki, Natsuki, Suzuki, Teruhiko, Pugacheva, Elena M., Vostrov, Alexander A., Morse, Herbert C., Loukinov, Dmitri, Lobanenkov, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149331/
https://ncbi.nlm.nih.gov/pubmed/21659515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243576
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