The Structural Complexity of the Human BORIS Gene in Gametogenesis and Cancer

BACKGROUND: BORIS/CTCFL is a paralogue of CTCF, the major epigenetic regulator of vertebrate genomes. BORIS is normally expressed only in germ cells but is aberrantly activated in numerous cancers. While recent studies demonstrated that BORIS is a transcriptional activator of testis-specific genes,...

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Detalhes bibliográficos
Main Authors: Pugacheva, Elena M., Suzuki, Teruhiko, Pack, Svetlana D., Kosaka-Suzuki, Natsuki, Yoon, Jeongheon, Vostrov, Alexander A., Barsov, Eugene, Strunnikov, Alexander V., Morse, Herbert C., Loukinov, Dmitri, Lobanenkov, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975627/
https://ncbi.nlm.nih.gov/pubmed/21079786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013872
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