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Internalization of Aggrecan G1 Domain Neoepitope ITEGE in Chondrocytes Requires CD44

Degradation of the cartilage proteoglycan aggrecan is one of the earliest events that occurs in association with osteoarthritis. Little is known concerning the fate of the residual N-terminal G1 domains of cleaved aggrecan; domains that remain bound to hyaluronan. In this study, 68–72-kDa bands repr...

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Detalhes bibliográficos
Main Authors: Ariyoshi, Wataru, Knudson, Cheryl B., Luo, Na, Fosang, Amanda J., Knudson, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975244/
https://ncbi.nlm.nih.gov/pubmed/20843796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129270
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