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CD44 and Hyaluronan Promote the Bone Morphogenetic Protein 7 Signaling Response in Murine Chondrocytes

OBJECTIVE: Cell–matrix interactions promote cartilage homeostasis. We previously found that Smad1, the transcriptional modulator of the canonical bone morphogenetic protein 7 (BMP-7) pathway, interacted with the cytoplasmic domain of CD44, the principal hyaluronan receptor on chondrocytes. To elucid...

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Main Authors: Luo, Na, Knudson, Warren, Askew, Emily B., Veluci, Roberta, Knudson, Cheryl B.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070509/
https://ncbi.nlm.nih.gov/pubmed/24497488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38388
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