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l-Arginine hydrochloride increases the solubility of folded and unfolded recombinant plasminogen activator rPA
l-Arginine hydrochloride (l-ArgHCl) was found to be an effective enhancer for in vitro protein refolding more than two decades ago. A detailed understanding of the mechanism of action, by which l-ArgHCl as co-solvent is capable to effectively suppress protein aggregation, while protein stability is...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975141/ https://ncbi.nlm.nih.gov/pubmed/20665695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.465 |
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