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Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18
Holocarboxylase synthetase (HCS) mediates the binding of biotin to lysine (K) residues in histones H2A, H3, and H4; HCS knockdown disturbs gene regulation, and decreases stress resistance and life span in eukaryotes. We tested the hypothesis that HCS interacts physically with histone H3 for subseque...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975038/ https://ncbi.nlm.nih.gov/pubmed/20688500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2010.04.001 |
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