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Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells
Holocarboxylase synthetase (HCS) plays an essential role in catalyzing the biotinylation of carboxylases and histones. Biotinylated carboxylases are important for the metabolism of glucose, lipids, and leucine; biotinylation of histones plays important roles in gene regulation and genome stability....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208029/ https://ncbi.nlm.nih.gov/pubmed/21764280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2011.03.007 |
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