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Biotin Regulates the Expression of Holocarboxylase Synthetase in the miR-539 Pathway in HEK-293 Cells(2)

Holocarboxylase synthetase (HCS) catalyzes the covalent binding of biotin to carboxylases and histones. In mammals, the expression of HCS depends on biotin, but the mechanism of regulation is unknown. Here we tested the hypothesis that microRNA (miR) plays a role in the regulation of the HCS gene. H...

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Detalhes bibliográficos
Main Authors: Bao, Baolong, Rodriguez-Melendez, Rocio, Wijeratne, Subhashinee S. K., Zempleni, Janos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924595/
https://ncbi.nlm.nih.gov/pubmed/20592104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.110.126359
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