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Biotin Regulates the Expression of Holocarboxylase Synthetase in the miR-539 Pathway in HEK-293 Cells(2)

Holocarboxylase synthetase (HCS) catalyzes the covalent binding of biotin to carboxylases and histones. In mammals, the expression of HCS depends on biotin, but the mechanism of regulation is unknown. Here we tested the hypothesis that microRNA (miR) plays a role in the regulation of the HCS gene. H...

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Hlavní autoři: Bao, Baolong, Rodriguez-Melendez, Rocio, Wijeratne, Subhashinee S. K., Zempleni, Janos
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Nutrition 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924595/
https://ncbi.nlm.nih.gov/pubmed/20592104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.110.126359
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