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Biotin Regulates the Expression of Holocarboxylase Synthetase in the miR-539 Pathway in HEK-293 Cells(2)

Holocarboxylase synthetase (HCS) catalyzes the covalent binding of biotin to carboxylases and histones. In mammals, the expression of HCS depends on biotin, but the mechanism of regulation is unknown. Here we tested the hypothesis that microRNA (miR) plays a role in the regulation of the HCS gene. H...

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Библиографические подробности
Главные авторы: Bao, Baolong, Rodriguez-Melendez, Rocio, Wijeratne, Subhashinee S. K., Zempleni, Janos
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Nutrition 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924595/
https://ncbi.nlm.nih.gov/pubmed/20592104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.110.126359
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