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Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
The kidney is the main physiologic source of erythropoietin (EPO) in the adult and responds to decreases in tissue oxygenation with increased EPO production. Although studies in mice with liver-specific or global gene inactivation have shown that hypoxia-inducible factor 2 (Hif-2) plays a major role...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974609/ https://ncbi.nlm.nih.gov/pubmed/20628150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-270322 |
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