Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia

Fanconi anemia (FA) is an inherited chromosomal instability syndrome characterized by bone marrow failure, myelodysplasia (MDS), and acute myeloid leukemia (AML). Eight FA proteins associate in a nuclear core complex to monoubiquitinate FANCD2/FANCI in response to DNA damage. Additional functions ha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pulliam-Leath, Anna C., Ciccone, Samantha L., Nalepa, Grzegorz, Li, Xiaxin, Si, Yue, Miravalle, Leticia, Smith, Danielle, Yuan, Jin, Li, Jingling, Anur, Praveen, Orazi, Attilio, Vance, Gail H., Yang, Feng-Chun, Hanenberg, Helmut, Bagby, Grover C., Clapp, D. Wade
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974601/
https://ncbi.nlm.nih.gov/pubmed/20606166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-240747
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados