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Monte Carlo Analysis of Neck Linker Extension in Kinesin Molecular Motors

Kinesin stepping is thought to involve both concerted conformational changes and diffusive movement, but the relative roles played by these two processes are not clear. The neck linker docking model is widely accepted in the field, but the remainder of the step – diffusion of the tethered head to th...

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Autors principals: Kutys, Matthew L., Fricks, John, Hancock, William O.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973807/
https://ncbi.nlm.nih.gov/pubmed/21079666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000980
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