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Neck Linker Length Determines the Degree of Processivity in Kinesin-1 and Kinesin-2 Motors

Defining the mechanical and biochemical determinates of kinesin processivity is important for understanding how diverse kinesins are tuned for specific cellular functions. Because transmission of mechanical forces through the 14–18 amino acid neck linker domain underlies coordinated stepping [1–6],...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shastry, Shankar, Hancock, William O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882250/
https://ncbi.nlm.nih.gov/pubmed/20471270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.03.065
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