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Kinesins with Extended Neck Linkers: A Chemomechanical Model for Variable-Length Stepping

We develop a stochastic model for variable-length stepping of kinesins engineered with extended neck linkers. This requires that we consider the separation in microtubule binding sites between the heads of the motor at the beginning of a step. We show that this separation is stationary and can be in...

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Detalles Bibliográficos
Main Authors: Hughes, John, Hancock, William O., Fricks, John
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105944/
https://ncbi.nlm.nih.gov/pubmed/21997362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-011-9697-6
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