A Phase I Study of a Tropism Modified Conditionally Replicative Adenovirus (CRAd) for Recurrent Gynecologic Malignancies

PURPOSE: To determine the maximum tolerated dose (MTD), toxicity spectrum, clinical activity, and biological effects of the tropism-modified infectivity-enhanced CRAd, Ad5-Δ24-RGD, in patients with gynecologic malignancies. EXPERIMENTAL DESIGN: Cohorts of eligible patients were treated daily for 3 d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kimball, Kristopher J., Preuss, Meredith A., Barnes, Mack N., Wang, Minghui, Siegal, Gene P., Wan, Wen, Kuo, Huichien, Saddekni, Souheil, Stockard, Cecil R., Grizzle, William E., Harris, Raymond D., Aurigemma, Rosemarie, Curiel, David T., Alvarez, Ronald D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970766/
https://ncbi.nlm.nih.gov/pubmed/20978148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0791
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