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Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment
Tumors induce new blood vessel growth primarily from host organ microvascular endothelial cells (ECs), and microvasculature differs significantly between the lung and liver. Vascular endothelial growth factor (VEGF or VEGF-A) promotion of tumor angiogenesis is thought to be mediated primarily by VEG...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970713/ https://ncbi.nlm.nih.gov/pubmed/20978198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1138 |
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