Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by modulating VEGFR2 signaling

Angiogenesis is central to both normal and pathologic processes. Endothelial cells (ECs) express O-glycoproteins that are believed to play important roles in vascular development and stability. Endomucin-1 (EMCN) is a type I O-glycosylated, sialic-rich glycoprotein, specifically expressed by venous...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Park-Windhol, Cindy, Ng, Yin Shan, Yang, Jinling, Primo, Vincent, Saint-Geniez, Magali, D’Amore, Patricia A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719432/
https://ncbi.nlm.nih.gov/pubmed/29215001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16852-x
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