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DLC1 negatively regulates angiogenesis in a paracrine fashion

The Rho GTPase activating protein DLC1 is a tumor suppressor that is often deleted in liver cancer and downregulated in other cancers. DLC1 regulates the actin cytoskeleton, cell shape, adhesion, migration, and proliferation through its RhoGAP activity and focal adhesion localization. In this study...

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Hlavní autoři: Shih, Yi-Ping, Liao, Yi-Chun, Lin, Yuan, Lo, Su Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970702/
https://ncbi.nlm.nih.gov/pubmed/20861185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1174
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