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BubR1- and Polo-Coated DNA Tethers Facilitate Poleward Segregation of Acentric Chromatids

The mechanisms that safeguard cells against chromosomal instability (CIN) are of great interest, as CIN contributes to tumorigenesis. To gain insight into these mechanisms, we studied the behavior of cells entering mitosis with damaged chromosomes. We used the endonuclease I-CreI to generate acentri...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Royou, Anne, Gagou, Mary E., Karess, Roger, Sullivan, William
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2969851/
https://ncbi.nlm.nih.gov/pubmed/20141837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.12.043
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