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BubR1- and Polo-Coated DNA Tethers Facilitate Poleward Segregation of Acentric Chromatids
The mechanisms that safeguard cells against chromosomal instability (CIN) are of great interest, as CIN contributes to tumorigenesis. To gain insight into these mechanisms, we studied the behavior of cells entering mitosis with damaged chromosomes. We used the endonuclease I-CreI to generate acentri...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2969851/ https://ncbi.nlm.nih.gov/pubmed/20141837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.12.043 |
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