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Drosophila BubR1 Is Essential for Meiotic Sister-Chromatid Cohesion and Maintenance of Synaptonemal Complex

The partially conserved Mad3/BubR1 protein is required during mitosis for the spindle assembly checkpoint (SAC). In meiosis, depletion causes an accelerated transit through prophase I and missegregation of achiasmate chromosomes in yeast [1], whereas in mice, reduced dosage leads to severe chromosom...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Malmanche, Nicolas, Owen, Stephanie, Gegick, Stephen, Steffensen, Soren, Tomkiel, John E., Sunkel, Claudio E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629868/
https://ncbi.nlm.nih.gov/pubmed/17702574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.07.042
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