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Isoxazole analogues bind the System x(c)(−) Transporter: Structure-activity Relationship and Pharmacophore Model
Analogues of amino methylisoxazole propionic acid (AMPA), were prepared from a common intermediate 12, including lipophilic analogues using lateral metalation and electrophilic quenching, and were evaluated at System x(c)(−). Both the 5-naphthylethyl-(16) and 5-naphthylmethoxymethyl-(17) analogues a...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967674/ https://ncbi.nlm.nih.gov/pubmed/19932968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.11.001 |
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