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The catalytic asymmetric addition of alkyl- and aryl-zinc reagents to an isoxazole aldehyde
Nucleophilic addition of alkyl- and aryl zinc reagents to a C(4) functionalized isoxazolyl aldehyde proceeded effectively with high enantioselectivity (85–94% e.e.). The amino alcohol catalyst (S)-2-piperidinyl-1,1,2-triphenyl ethanol (10) afforded the (R)-product 2b, as established by x-ray crystal...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2598407/ https://ncbi.nlm.nih.gov/pubmed/19812681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.07.169 |
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