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Catalytic asymmetric direct aldol reaction of α-alkyl azlactones and aliphatic aldehydes
An unprecedented highly diastereoselective and enantioselective aldol reaction of α-alkyl azlactones and aliphatic aldehydes was achieved with cinchona alkaloid catalysts. To our knowledge, this reaction provides the first useful catalytic asymmetric access toward β-hydroxy-α-amino acids bearing alk...
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| Publicado en: | Chem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762611/ https://ncbi.nlm.nih.gov/pubmed/26918108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02116b |
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