Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function

Regulatory T cells (Tregs) are required for the maintenance of immune homeostasis as first clearly described by Herman Waldmann’s laboratory. Dysfunction of Treg cells also leads to fatal autoimmunity in humans and mice. Conversely, the activation of different classes of Tregs operative systemically...

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Bibliographic Details
Main Authors: Xiao, Yan, Li, Bin, Zhou, Zhaocai, Hancock, Wayne W., Zhang, Hongtao, Greene, Mark I.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967626/
https://ncbi.nlm.nih.gov/pubmed/20869864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.08.013
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