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Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs
Histone/protein deacetylases (HDACs) decrease histone and protein acetylation, typically leading to suppression of gene transcription and modulation of various protein functions. We found significant differences in expression of HDAC before and after stimulation of human T regulatory (Treg) and T ef...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917523/ https://ncbi.nlm.nih.gov/pubmed/20478744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.04.018 |
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