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Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs
Histone/protein deacetylases (HDACs) decrease histone and protein acetylation, typically leading to suppression of gene transcription and modulation of various protein functions. We found significant differences in expression of HDAC before and after stimulation of human T regulatory (Treg) and T ef...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917523/ https://ncbi.nlm.nih.gov/pubmed/20478744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.04.018 |
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