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HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms
Vpu is a small integral membrane protein encoded by HIV-1 and some SIV isolates. The protein is known to induce degradation of the viral receptor molecule CD4 and to enhance the release of newly formed virions from the cell surface. Vpu accomplishes these two functions through two distinct mechanism...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967615/ https://ncbi.nlm.nih.gov/pubmed/20858517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2010.08.002 |
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