Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis

Aurora-B is a component of the Chromosomal Passenger Complex (CPC) required for correct spindle-kinetochore attachments during chromosome segregation and for cytokinesis. The chromatin factors that recruit the CPC to centromeres are unknown, however. Here we show that phosphorylation of Histone-H3 T...

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Main Authors: Wang, Fangwei, Dai, Jun, Daum, John R., Niedzialkowska, Ewa, Banerjee, Budhaditya, Stukenberg, P. Todd, Gorbsky, Gary J., Higgins, Jonathan M.G.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967368/
https://ncbi.nlm.nih.gov/pubmed/20705812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189435
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