Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres

Survivin, a subunit of the chromosome passenger complex (CPC), binds the N-terminal tail of histone H3, which is phosphorylated on T3 by Haspin kinase, and localizes the complex to the inner centromeres. We used x-ray crystallography to determine the residues of Survivin that are important in bindin...

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Bibliographic Details
Main Authors: Niedzialkowska, Ewa, Wang, Fangwei, Porebski, Przemyslaw J., Minor, Wladek, Higgins, Jonathan M. G., Stukenberg, P. Todd
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327328/
https://ncbi.nlm.nih.gov/pubmed/22357620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0904
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