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Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres
Survivin, a subunit of the chromosome passenger complex (CPC), binds the N-terminal tail of histone H3, which is phosphorylated on T3 by Haspin kinase, and localizes the complex to the inner centromeres. We used x-ray crystallography to determine the residues of Survivin that are important in bindin...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327328/ https://ncbi.nlm.nih.gov/pubmed/22357620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0904 |
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