Loading...
CRL4(Cdt2) Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation
PR-Set7/Set8 is a cell cycle-regulated enzyme that monomethylates lysine 20 of histone H4 (H4K20). Set8 and monomethylated H4K20 are virtually undetectable during G1 and S phases of the cell cycle but increase in late S and in G2. We identify CRL4(Cdt2) as the principal E3 ubiquitin ligase responsib...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966975/ https://ncbi.nlm.nih.gov/pubmed/20932471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.09.014 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|