Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII

BACKGROUND: Heparanase is an endo-β-D-glucuronidase dominantly involved in tumor metastasis and angiogenesis. Recently, we demonstrated that heparanase is involved in the regulation of the hemostatic system. Our hypothesis was that heparanase is directly involved in activation of the coagulation cas...

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Bibliografiska uppgifter
Huvudupphovsmän: Nadir, Yona, Brenner, Benjamin, Fux, Liat, Shafat, Itay, Attias, Judith, Vlodavsky, Israel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ferrata Storti Foundation 2010
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966916/
https://ncbi.nlm.nih.gov/pubmed/20634491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.023713
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