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Clinical Significance of Urine Heparanase in Bladder Cancer Progression

Heparanase is an endo-β-glucuronidase capable of cleaving heparan sulfate (HS), an activity implicated in tumor metastasis. Heparanase expression is upregulated in primary human tumors, correlating with reduced post operative survival and elevated microvessel density. An ELISA method was used to qua...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shafat, Itay, Pode, Dov, Peretz, Tamar, Ilan, Neta, Vlodavsky, Israel, Nisman, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244687/
https://ncbi.nlm.nih.gov/pubmed/18283334
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