Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation

BACKGROUND: Impaired regulation of hepcidin in response to iron is the cause of genetic hemochromatosis associated with defects of HFE and transferrin receptor 2. However, the role of these proteins in the regulation of hepcidin expression is unclear. DESIGN AND METHODS: Hepcidin expression, SMAD an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Poli, Maura, Luscieti, Sara, Gandini, Valentina, Maccarinelli, Federica, Finazzi, Dario, Silvestri, Laura, Roetto, Antonella, Arosio, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966904/
https://ncbi.nlm.nih.gov/pubmed/20634490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.027003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados