Novel Aptamer Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase

Primer-template–based double-stranded nucleic acids capable of binding human immunodeficiency virus reverse transcriptase (HIV-RT) with high affinity were used as starting material to develop small single-stranded loop-back DNA aptamers. The original primer-templates were selected using a SELEX (Sys...

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Bibliographic Details
Main Authors: DeStefano, Jeffrey J., Nair, Gauri R.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2008
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966829/
https://ncbi.nlm.nih.gov/pubmed/18637731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2008.0103
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