The orientation of binding of human immunodeficiency virus reverse transcriptase on nucleic acid hybrids.
The binding of HIV reverse transcriptase (RT) to heteroduplexes was examined using a substrate consisting of a 42 nt chimeric nucleic acid composed. (5'-->3') of 23 nt of RNA and 19 of DNA. This chimera was hybridized to an internal region of a relatively long complementary DNA or RNA. When the chim...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1995
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307308/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3901 |
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