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Msh6 Protects Mature B Cells from Lymphoma by Preserving Genomic Stability
Most human B-cell non-Hodgkin’s lymphomas arise from germinal centers. Within these sites, the mismatch repair factor MSH6 participates in antibody diversification. Reminiscent of the neoplasms arising in patients with Lynch syndrome III, mice deficient in MSH6 die prematurely of lymphoma. In this s...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Investigative Pathology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966815/ https://ncbi.nlm.nih.gov/pubmed/20934970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100234 |
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