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Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: a redox/polyamine-dependent effect

Non-steroidal anti-inflammatory drugs such as sulindac are promising chemoprevention agents against colon cancer, but their weak potency and side effects limit their use for both chemoprevention and chemotherapy. Here, we evaluated the effect of a new sulindac derivative, phospho-sulindac or OXT-922...

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Autors principals: Huang, Liqun, Zhu, Caihua, Sun, Yu, Xie, Gang, Mackenzie, Gerardo G., Qiao, George, Komninou, Despina, Rigas, Basil
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966552/
https://ncbi.nlm.nih.gov/pubmed/20627873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq149
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