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Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: a redox/polyamine-dependent effect

Non-steroidal anti-inflammatory drugs such as sulindac are promising chemoprevention agents against colon cancer, but their weak potency and side effects limit their use for both chemoprevention and chemotherapy. Here, we evaluated the effect of a new sulindac derivative, phospho-sulindac or OXT-922...

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Detalhes bibliográficos
Main Authors: Huang, Liqun, Zhu, Caihua, Sun, Yu, Xie, Gang, Mackenzie, Gerardo G., Qiao, George, Komninou, Despina, Rigas, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966552/
https://ncbi.nlm.nih.gov/pubmed/20627873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq149
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