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Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling
Dendritic cells (DCs) comprise distinct functional subsets including CD8(−) and CD8(+) classical DCs (cDCs) and interferon-secreting plasmacytoid DCs (pDCs). The cytokine Flt3 ligand (Flt3L) controls the development of DCs, and is particularly important for the pDC, CD8(+) cDC and their CD103(+) tis...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966531/ https://ncbi.nlm.nih.gov/pubmed/20933441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.012 |
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