Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling

Dendritic cells (DCs) comprise distinct functional subsets including CD8(−) and CD8(+) classical DCs (cDCs) and interferon-secreting plasmacytoid DCs (pDCs). The cytokine Flt3 ligand (Flt3L) controls the development of DCs, and is particularly important for the pDC, CD8(+) cDC and their CD103(+) tis...

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Detalhes bibliográficos
Main Authors: Sathaliyawala, Taheri, O’Gorman, William E., Greter, Melanie, Bogunovic, Milena, Konjufca, Vjollca, Hou, Z. Esther, Nolan, Garry P., Miller, Mark J., Merad, Miriam, Reizis, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966531/
https://ncbi.nlm.nih.gov/pubmed/20933441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.012
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