Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine

Dendritic cells (DCs) in tissues and lymphoid organs comprise distinct functional subsets that differentiate in situ from circulating progenitors. Tissue-specific signals that regulate DC subset differentiation are poorly understood. We report that DC-specific deletion of the Notch2 receptor caused...

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Main Authors: Lewis, Kanako L., Caton, Michele L., Bogunovic, Milena, Greter, Melanie, Grajkowska, Lucja T., Ng, Dennis, Klinakis, Apostolos, Charo, Israel F., Jung, Steffen, Gommerman, Jennifer L., Ivanov, Ivaylo I., Liu, Kang, Merad, Miriam, Reizis, Boris
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225703/
https://ncbi.nlm.nih.gov/pubmed/22018469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.08.013
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