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Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells
The IRF8-dependent subset of classical dendritic cells (cDCs), termed cDC1, is important for cross-priming cytotoxic T cell responses against pathogens and tumors. Culture of hematopoietic progenitors with DC growth factor FLT3 ligand (FLT3L) yields very few cDC1s (in humans) or only immature “cDC1-...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6063084/ https://ncbi.nlm.nih.gov/pubmed/29925006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.068 |
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