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Protein-Protein Interactions in Transcription: A Fertile Ground for Helix Mimetics

Designed ligands that inhibit protein-protein interactions involved in gene expression are valuable as reagents for genomics research and as leads for drug discovery efforts. Selective modulation of protein-protein interactions has proven to be a daunting task for synthetic ligands; however, the las...

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Hlavní autoři: Guarracino, Danielle A., Bullock, Brooke N., Arora, Paramjit S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966508/
https://ncbi.nlm.nih.gov/pubmed/20882600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21546
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