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In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics

Development of small-molecule inhibitors of protein–protein interactions is a fundamental challenge at the interface of chemistry and cancer biology. Successful methods for design of protein–protein interaction inhibitors include computational and experimental high-throughput and fragment-based scre...

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Autori principali: Lao, Brooke Bullock, Grishagin, Ivan, Mesallati, Hanah, Brewer, Thomas F., Olenyuk, Bogdan Z., Arora, Paramjit S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040591/
https://ncbi.nlm.nih.gov/pubmed/24821806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402393111
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