Carvedilol as a potential novel agent for the treatment of Alzheimer’s disease

Oligomeric β-amyloid (Aβ) has recently been linked to synaptic plasticity deficits, which play a major role in progressive cognitive decline in Alzheimer’s disease (AD). Here we present evidence that chronic oral administration of carvedilol, a nonselective β-adrenergic receptor blocker, significant...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Ono, Kenjiro, Dickstein, Dara L., Arrieta-Cruz, Isabel, Zhao, Wei, Qian, Xianjuan, Lamparello, Ashley, Subnani, Rakesh, Ferruzzi, Mario, Pavlides, Constantine, Ho, Lap, Hof, Patrick R., Teplow, David B., Pasinetti, Giulio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966505/
https://ncbi.nlm.nih.gov/pubmed/20579773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.05.004
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