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Protective Roles of Intestinal Microbiota derived Short Chain Fatty Acids in Alzheimer’s Disease-type Beta-Amyloid Neuropathological Mechanisms

BACKGROUND: Dietary fibers are metabolized by gastrointestinal (GI) bacteria into short-chain fatty acids (SCFAs). We investigated the potential role of these SCFAs in β-amyloid (Aß) mediated pathological processes that play key roles in Alzheimer’s disease (AD) pathogenesis. RESEARCH DESIGN AND MET...

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Detalhes bibliográficos
Publicado no:Expert Rev Neurother
Main Authors: Ho, Lap, Ono, Kenjiro, Tsuji, Mayumi, Mazzola, Paolo, Singh, Risham, Pasinetti, Giulio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958896/
https://ncbi.nlm.nih.gov/pubmed/29095058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14737175.2018.1400909
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