Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

BACKGROUND: Dimebon is a retired non-selective antihistamine drug currently being investigated as a therapeutic agent for the treatment of Alzheimer's disease (AD). Results from several completed clinical trials are mixed and contradictory. Proper interpretations of these clinical observations,...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Ferruzzi, Mario G, Varghese, Merina, Qian, Xianjuan, Cheng, Alice, Xie, Mathew, Zhao, Wei, Ho, Lap, Pasinetti, Giulio M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035024/
https://ncbi.nlm.nih.gov/pubmed/21247479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-7
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