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Protective Efficacy of BCG Overexpressing an L,D-Transpeptidase against M. tuberculosis Infection

BACKGROUND: M. bovis Bacille Calmette-Guérin (BCG), currently the only available vaccine against tuberculosis (TB), fails to adequately protect individuals from active and latent TB infection. New vaccines are desperately needed to decrease the worldwide burden of TB. METHODS AND FINDINGS: We create...

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Autori principali: Nolan, Scott T., Lamichhane, Gyanu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966435/
https://ncbi.nlm.nih.gov/pubmed/21048936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013773
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