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Protective Efficacy of BCG Overexpressing an L,D-Transpeptidase against M. tuberculosis Infection

BACKGROUND: M. bovis Bacille Calmette-Guérin (BCG), currently the only available vaccine against tuberculosis (TB), fails to adequately protect individuals from active and latent TB infection. New vaccines are desperately needed to decrease the worldwide burden of TB. METHODS AND FINDINGS: We create...

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Detalles Bibliográficos
Main Authors: Nolan, Scott T., Lamichhane, Gyanu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966435/
https://ncbi.nlm.nih.gov/pubmed/21048936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013773
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