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Protective Efficacy of BCG Overexpressing an L,D-Transpeptidase against M. tuberculosis Infection

BACKGROUND: M. bovis Bacille Calmette-Guérin (BCG), currently the only available vaccine against tuberculosis (TB), fails to adequately protect individuals from active and latent TB infection. New vaccines are desperately needed to decrease the worldwide burden of TB. METHODS AND FINDINGS: We create...

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Autors principals: Nolan, Scott T., Lamichhane, Gyanu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966435/
https://ncbi.nlm.nih.gov/pubmed/21048936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013773
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