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Protective Efficacy of BCG Overexpressing an L,D-Transpeptidase against M. tuberculosis Infection

BACKGROUND: M. bovis Bacille Calmette-Guérin (BCG), currently the only available vaccine against tuberculosis (TB), fails to adequately protect individuals from active and latent TB infection. New vaccines are desperately needed to decrease the worldwide burden of TB. METHODS AND FINDINGS: We create...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nolan, Scott T., Lamichhane, Gyanu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966435/
https://ncbi.nlm.nih.gov/pubmed/21048936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013773
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